Liquid chromatography-high-resolution mass spectrometry for pesticide residue analysis in fruit and vegetables: Screening and quantitative studies.
M.M. Gómez-Ramos, C. Ferrer, O. Malato, A. Agüera, A.R. Fernández-Alba
Journal of Chromatography A, 1287 (2013) 24- 37
Abstract
This work reviews the current state-of-the-art of liquid chromatography coupled to high-resolution mass spectrometry (LC-HRMS) techniques applied to the analysis of pesticides in fruit-based and vegetable based matrices. Nowadays,simultaneous trace analysis of hundreds of pesticides from different classes is required, preferably in just one run. The most commonly used QqQ-MS technology presents certain limitations in its application in a cost and effective way when analyzing a large number of pesticides. Thus, this review includes HRMS technology as a reliable complementary alternative allowing the analysis of a wide range of pesticides in food. Its capabilities and limitations in identifying, confirming and quantifying pesticides are discussed. HRMS instruments can adequately address such issues; however, the main drawbacks are as a result of insufficient prior optimization of the operational parameters during nontarget analysis in full-scan mode and due to software shortcomings.
Copyright © 2012 Elsevier B.V. All rights reserved.
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Published 02-05-2013, 13:06:31
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